Animal House Facility


The animal house facility is available to conduct preclinical research including pharmacodynamic, pharmacokinetic studies including toxicity testing. Qualified veterinarian and technical personnel are always at hand to help carry out research and keep it in accordance with the standards established by the Committee for the Purpose of Control and Supervision of Experiments on Animals (CPCSEA).

The CPCSEA approved animal house for rats, mice, guinea pigs and rabbits with all facilities and frogery for housing frogs is available. The animal studies that are carried includes;

Antioxidant Studies:
  • Formulation, characterization and evaluation of liposomes loaded with bioflavonoid and tryptamine derivative for antioxidant activity
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  • Isolation Characterization and hepatoprotective and antioxidant activity from a plant of Cucurbitaceae family
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  • Isolation, Characterization & evaluation of hepatoprotective & antioxidant activity from the plant curcubitaceae
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  • Formulation, Characterization & evaluation of liposomes loaded with biflavonoid and tryptamine derivative for antioxidant activity
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  • Phytochemical investigation and evaluation of anticancer activity of Adenoon indicum L. leaves

 

Analgesic, Anti-inflammatory Studies:
  • Evaluation of analgesic activity of the herbal formulation
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  • Development of novel topical gel formulation containing  Hamiltonia surveolens for wound healing activity
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  • Phytochemical investigation and evaluation of anticancer activity of Adenoon indicum L. leaves
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  • Preparation and evaluation of new polyherbal formulation for their wound healing activity
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  • Development of topical formulation containing Allophyllus cobbe L. for wound healing activity
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  • Investigation of antiarthritic potential of Annona squamosa and Citrus sinensis
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  • Phytochemical investigation of eleusine species for possible biological activities
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  • Evaluation of anti-inflammatory and analgesic activity of the synthetic formulation
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  • Modification of physicochemical properties of active pharmaceutical ingredients by crystal engineering (analgesic & anti-inflammatory)
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  • Evaluation of anti-inflammatory activity of the herbal formulation
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  • Evaluation of analgesic activity of the herbal formulation
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  • Development and studies on in-vitro, in-vivo correlation of polyhydroxybutyrate based extended release tablet Ibuprofen
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  • Development and studies in in-vitro, in-vivo correlation of new soft gelatin capsule containing oil-in-oil emulsion of Ibuprofen

 

Anti-diabetics Studies:
  • Investigation of antidiabetic activity of Caralumma fibriata
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  • Development of novel animal model for type-2 diabetics model
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  • Evaluation of antidiabetic activity of some Indian medicinal plant

 

Anticancer Studies:
  • Phytochemical investigation and evaluation of anticancer activity of Adenoon indicum L. leaves
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  • Development and characterization of anticancer drug loaded erythrocytes membrane vesicles for tumor targeting
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  • Development and evaluation of herbal drug delivery system for chemoprophylaxis of colorectal cancer
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  • Development of capecitabine loaded nanoerythrosomes for colorectal cancer targeting

 

Anti-Urolithiatic Studies:
  • Study on antiurolithiatic activity of Sphearanthus indicus Linn
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  • Investigation of antiurolithiatic potential of Annona Squamosa & Citrus sinesis
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  • Investigation of antiurolithiatic activity of Canna indica plant
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  • Phytochemical investigation and pharmacological evaluation of medicinal plant for antiurilithisis

 

Anti-Hyperlipidemic Studies:
  • Investigation of antihyperlipidemic activity of Caralumma fibriata
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  • Evaluation of co-crystal of fenofibrate for stability and in-vivo efficacy

 

Anti-HIV Drug Studies:
  • Development and evaluation of oral emulsion system for poorly bioavailable Anti-HIV drug

 

Anti-obesity Studies:
  • Anti-obesity Studies of a herbal tablet

 

Pharmacokinetics Study:
  • Screening potential of polymer some in drug targeting and controlled drug delivery
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  • Development of lipid based topical formulation for antimicrobial activity
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  • Preparation and evaluation of nanoparticulate drug delivery system of certain drug
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  • Development of solid micro-emulsifying drug delivery system of cardiovascular drug for enhance bioavailability
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  • Microencapsulation by spray drying for stability enhancement of rabeprazole
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  • Design and development of mucoadhesive fast disintegrating sublingual tablet for rapid absorption of picroxicam
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  • Disolution rate enhancement and In-Vitro bioavailability study of lornoxicam solid dispersion prepared by spray drying technique
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  • Design, development and characterization of delayed release multiunit particulate system of esmoprazole magnesium
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  • Development of controlled porosity osmotic pump tablet for oral administration of metformin and glipizide
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  • Development of modified release biphasic compressed tablet
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  • Solid self micro-emulsifying drug delivery system of poorly soluble drug for enhancement of bioavailability
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  • Micro-emulsion based in situ gel of ciprifloxacine for ophthalmic drug delivery
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  • Novel solid self micro-emulsifying drug delivery system for enhanced bioavailability of poorly aqueous soluble drug
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  • Screeing natural gum for their potential sustaining release from matrix tablet of Verapamil hydrochloride
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  • Development of solid self micro-emulsifying drug delivery system of ritonavir for bioavailability enhancement
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  • Development of oil in oil emulsion for topical drug delivery of antifungal drug
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  • Development of oro-disersible tablet of atorvastatin calcium using hot melt extrusion
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  • Development of non aqueous emulsion based antiwrinkle formulation containing vitamin C
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  • Development of polyhydroxylic based non aqueous microemulsion for antifungal drug delivery
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  • Quality standardization and toxicity study of Garlicon-A cardivascular formulation
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  • Development and studies on in-vitro, in-vivo correlation of polyhydroxybutyrate based extended release tablet Ibuprofen
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  • Development and studies in in-vitro, in-vivo correlation of new soft gelatin capsule containing oil-in-oil emulsion of Ibuprofen
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  • Development of floating microsphere of antiulcer drug as a gastro-retentive drug delivery system
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  • Development and evaluation of oral emulsion system for poorly bioavailable Anti-HIV drug
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  • Analytical method development for the simultaneous quantification of ternary mixture containing anticonvulsant drugs with biological activity
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  • Formulation, characterization & evaluation of liposomes loaded with biflavonoid and tryptamine derivative for antioxidant activity
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  • Polyacrylic acid docetaxel conjugate micelles: application in tumor targeting
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  • Development and characterization of anticancer drug loaded erythrocytes membrane vesicles for tumor targeting
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  • Development and evaluation of herbal drug delivery system for chemoprophylaxis of colorectal cancer
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  • Evaluation of rectal mucosal irritation study of herbal rectal microbicide
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  • Evaluation of vaginal mucosal irritation study of herbal vaginal microbicide
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  • Study on pharmacokinetics of novel fenofibrate/ atorvastatin nanoformulation in comparison with marketed formulation
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  • Fluvastatin-loaded micelle: role in controlling tumor development and progression
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  • Development of capecitabine loaded nanoerythrosomes for colorectal cancer targeting
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  • Composition of terbinafine HCL nanosuspension for ocular drug delivery
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  • Comparative study of adsorbent carrier and porous polymer: application in improving oral kinetics (Kinetics By HPLC)
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  • Solubilizing agents: Screening for improved oral solubility  (Kinetics By HPLC)
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  • Preparation of phospholipid drug complex for improved oral bioavailability (Kinetics By HPLC)
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